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chromogenic plasmin substrate equivalent  (Innovative Research Inc)


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    Innovative Research Inc chromogenic plasmin substrate equivalent
    Chromogenic Plasmin Substrate Equivalent, supplied by Innovative Research Inc, used in various techniques. Bioz Stars score: 93/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmin+chromogenic+substrate/pm40440389-354-32-39?v=Innovative+Research+Inc
    Average 93 stars, based on 9 article reviews
    chromogenic plasmin substrate equivalent - by Bioz Stars, 2026-08
    93/100 stars

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    Plasmin generation of tPA beads. Plasmin generation was measured using <t>chromogenic</t> substrate S‐2251, glu‐plasminogen, and 2.25 mU/mL tPA activity with (a) free tPA, (b) 0.1 μm t‐PA beads, or (c) 1 μm tPA beads and its co‐factors fibrinogen or fibrin degradation product (FDP) at 37°C. Each line and shaded region represent the average and standard deviation of n = 3. (d) Slope of the reaction curves at 50% of the maximum absorbance for each condition. Bars and error bars represent the average and standard deviation of n = 3. * p < 0.001 represents the significant difference between matching tPA conditions for a given co‐factor (comparison of grouped blue, orange, and green bars). Δ p < 0.001 represents the significant difference between co‐factors for a given tPA condition (comparison of like colored bars).
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    Plasmin generation of tPA beads. Plasmin generation was measured using chromogenic substrate S‐2251, glu‐plasminogen, and 2.25 mU/mL tPA activity with (a) free tPA, (b) 0.1 μm t‐PA beads, or (c) 1 μm tPA beads and its co‐factors fibrinogen or fibrin degradation product (FDP) at 37°C. Each line and shaded region represent the average and standard deviation of n = 3. (d) Slope of the reaction curves at 50% of the maximum absorbance for each condition. Bars and error bars represent the average and standard deviation of n = 3. * p < 0.001 represents the significant difference between matching tPA conditions for a given co‐factor (comparison of grouped blue, orange, and green bars). Δ p < 0.001 represents the significant difference between co‐factors for a given tPA condition (comparison of like colored bars).

    Journal: Bioengineering & Translational Medicine

    Article Title: Micrometer‐scale tPA beads amplify plasmin generation for enhanced thrombolytic therapy

    doi: 10.1002/btm2.70012

    Figure Lengend Snippet: Plasmin generation of tPA beads. Plasmin generation was measured using chromogenic substrate S‐2251, glu‐plasminogen, and 2.25 mU/mL tPA activity with (a) free tPA, (b) 0.1 μm t‐PA beads, or (c) 1 μm tPA beads and its co‐factors fibrinogen or fibrin degradation product (FDP) at 37°C. Each line and shaded region represent the average and standard deviation of n = 3. (d) Slope of the reaction curves at 50% of the maximum absorbance for each condition. Bars and error bars represent the average and standard deviation of n = 3. * p < 0.001 represents the significant difference between matching tPA conditions for a given co‐factor (comparison of grouped blue, orange, and green bars). Δ p < 0.001 represents the significant difference between co‐factors for a given tPA condition (comparison of like colored bars).

    Article Snippet: Purified human lys‐plasmin (cat# IHUPLMLYS1MG) and plasmin chromogenic substrate (cat# IAFPLMCGSLY25MG) were obtained from Innovative Research (Novi, MI).

    Techniques: Activity Assay, Standard Deviation, Comparison